2 years ago

STAT inhibitor ABT-263 Omecamtiv mecarbil

nositol 4,5 bisphosphate
(PIP2
) to inositol triphosphate (IP3
)
and diacylglycerol (DAG). IP3
mediates
release of Ca
2+
from intracellular stores
which is measured within the FLIPR-based
te read more...

2 years ago

STAT inhibitor ABT-263 Omecamtiv mecarbil

nhibition of B cell activation.Introduction
Phenotypic screening has reemerged as being a beneficial strategy
to drug discovery. Even so, establishing ideal, robust
screening platforms which might be validated and amenable to high read more...