We examined the effects of mega CD40 ligand (mega
CD40L) and crosslinking CD40R with anti-CD40 on LFA-1/
ICAM-1 adhesion. Certainly, both mega CD40L and anti-
CD40R elicited LFA-1/ICAM-1 adhesion while in the EPIC assay
(Fig. read more...
The syk/BTK inhibitor
R406 displayed potency while in the micromolar range in both the
FLIPR and EPIC assays. The kind II inhibitor, compound 6,
displayed tiny inhibition in each cell-based assays. Also,
the covalent inhibi read more...