Dimethyl Sulfate is used as one of the important chemical materials, a kind of important met widely used in chemical, pharmaceutical, pesticide, war industry, dye, perfume and so on, plays an important role in national economy.
Dimethyl sulfate can affect the base specific cleavage of guanine in DNA by rupturing the imidazole rings present in guanine. This process can be used to determine base sequencing, cleavage on the DNA chain, and other applications.
Dimethyl sulfate also methylates adenine in single stranded portions of DNA (e.g., those with proteins like RNA polymerase progressively melting and reannealing the DNA). Upon reannealing, these methyl groups interfere with adenine guanine base pairing. Nuclease S1 can then be used to cut the DNA in single stranded regions (anywhere with a methylated adenine). This is an important technique for analyzing protein DNA interactions.
Nanjing Xiancheng Chemical Industrial Co., Ltd was founded on the basis of strong R&D ability and advanced production equipments.At present, Nanjing Xiancheng is a leading and professional manufacturer specializing in the production and development of thio chemicals, fine chemicals and pharmaceutical intermediates, mainly produce dimethyl disulfide, dimethyl sulfate, methanesulfonic acid, methanesulfonyl chloride.
Nanjing Xiancheng is not only the major qualified supplier of SINOPEC and PETRO CHINA, but also exports to many countries, establishing long term business relationship with the clients from Middle East, South East Asia, Europe and US. Our company is active in the seeking of support and cooperation with friends from all walks.
If you want to know more about Dimethyl Sulfate, please come and click our website. We promise you will get reply within 24 hours.
Nanjing Xiancheng Chemical Industrial Co., Ltd