Urine is to date the most classically used matrix for the assessment of human exposure to pesticides. Although this matrix allows for the detection of several compounds, mainly metabolites, the kinetics of urinary compounds makes it A-740003 representative of recent exposure only for most chemicals  and . Thanks to progress in analytical sciences which led to significant improvement in methods sensitivity, growing interest is currently observed in hair analysis for the detection of organic pollutants . Hair enables to detect both metabolites and parent compounds, with windows of detection generally corresponding to several months, depending on hair sample length. Due to the different nature of urine and hair, which are liquid and solid respectively, and also partially to the prejudice on the compounds detectable therein, no comparison of the respective possibilities of both matrices with regard to the biomonitoring of human exposure to organic pollutants has been performed so far.