Scheme 1. Mechanism for the oxidation of CAL-101 by TEACC.Figure optionsDownload full-size imageDownload as PowerPoint slide
4.6. Effect of solvent
The rate of oxidation of methionine was determined in 19 different organic solvents. The choice of the solvents was limited by the solubility of TEACC and its reactivity with methionine. There was no noticeable reaction with the solvents chosen. The values of k2 at 303 K are recorded in Table 3.
Second-order rate constants for the oxidation of absorption Methionine by TEACC at 303 K in various solvents.Solventsk2104 (dm−3 mol−1 s−1)Solventsk2103 (dm−3 mol−1 s−1)Chloroform35.8Toluene8.71,2-Dichloroethane29.3Acetophenone30.5Dichloromethane34.0THF15.0DMSO80.2tert-Butyl alcohol22.0Acetone27.01,4-Dioxane16.7DMF43.91,2-Dimethoxyethane10.0Butanone22.7Carbon disulfide5.7Nitrobenzene31.7Acetic acid13.0Benzene10.9Ethyl acetate13.3Cyclohexane1.7Full-size tableTable optionsView in workspaceDownload as CSV