All wood-rot fungi growing in OMW effectively reduced phenol content in the effluent (more than 60% reduction of total phenolics), with the exception of L. castoreus, P. chrysosporium and T. panuoides strains, which decreased phenolics to a lesser degree ( Fig. 2). All Pleurotus species tested were top degraders of phenolics by exhibiting decrease of pertinent values by up to 95% (i.e. P. ostreatus LGAM015). Very high reductions (>80%) in total phenolics were also observed for several other white-rot fungi, e.g. A. biennis, D. quercina, H. erinaceus (strain LGAM311), H. lateritium, I. andersonii, T. hirsuta, T. versicolor and T. lacteus ( Fig. 2), thus evidencing that within this group of microorganisms there is a Darunavir of strains particularly effective in degrading phenolic compounds. As regards to OMW decolorization, most of the tested strains presented a similar behavior to that exhibited for dephenolization ( Fig. 3). Hence, Pleurotus species, A. biennis, D. quercina, H. erinaceus (strain LGAM311), I. andersonii, T. hirsuta and T. versicolor were the top color reducers (55–70% color decrease in respect to the control). The ability of Pleurotus and Trametes spp. for decolorizing OMW is well established ( Dhouib et al., 2006 and Ntougias et al., 2012); all other species have not been previously examined for OMW treatment. On the other hand, an increase in the color of the medium was observed in the cultures of L. castoreus and T. panuoides ( Fig. 3), most probably because of oxidation of phenolic compounds ( Thurston, 1994) and the absence of any notable enzymatic activities in these particular strains ( Fig. 4). A significant correlation was revealed between total phenolic content and OMW color (r = 0.875, p < 0.01) ( Table 1), which is in accordance with the outcome of past studies on other white-rot fungi ( Koutrotsios and Zervakis, 2014 and Sayadi et al., 2000), confirming thus that for this group of organisms OMW decolorization is mainly achieved through dephenolization of the effluent.