The internal partitions of pipelines are divided into situation in crude oil pipes is additional vulnerable to inside corrosion go to website due to the fact of the existence of produced water which is denser than oil, very low in Oxygen content material, with the existence of a assortment of microorganisms. Organic and natural corrosion inhibitors have been greatly used in fixing corrosion difficulties because of their availability and ease of software. Natural and organic corrosion inhibitors are typically composed of hetero-atoms such as Nitrogen, Sulfur and Oxygen in conjugate systems. The heteroatom is used for adsorption on the surface of the metal. Exploration effects have shown that compounds that contains the next purposeful groups. These chemical inhibitors are either chemisorbed or physiosorbed on the metal area. The construction activity connection and the adsorption info for particular oil industry corrosion inhibitors have been utilized to calculate the kinetics-thermodynamic parameters and predict their mode of adsorption. Literature displays that compounds that are chemisorbed onto the electrode can yield incredibly fantastic film persistency. A good deal of exploration has been carried out on corrosion inhibition with fascinating conclusions which has led to much better knowledge of corrosion and its inhibition. However, most of the inhibitors presently in use in industry poison the environment. There is look for for much less unfavorable affect corrosion inhibitors which can compete favorable with current industrial inhibitors. The corrosion of iron may possibly commence, relying on the pre-background of the metal and environmental problems, by means of unique reaction routes. Consequently multi-constituent substances, in some circumstances are expected for successful corrosion inhibition synergistic result. In the interior walls of pipelines, the put together result of corrosive components and microbial consortia necessitates an inhibitor with the two anti-oxidative and antimicrobial potentials. Corrosion inhibition effectiveness can be described as a function of inhibitors ability to be adsorbed on the metal area which is a perform of physio-chemical parameters of the inhibitor and the corrosive environment. The corrosion inhibition capability of the mixture of Sulfadoxine and Pyrimethamine was investigated and in comparison with an inhibitor presently in use in the petroleum sector NSC 713200 named S-Industrial Inhibitor . The presence of sulfur, nitrogen, chlorine and fragrant ring framework in Sulfadoxine Pyrimethamine framework will most likely confer a multifunctional edge on it that is the two anti-corrosion and anti-microbial actions. These material have been utilised as medicine in opposition to malaria an oxidative tension disorder in the ratio. The helpful software of this substance can be improved by investigating its corrosion inhibition potential. Each compounds have the essential heteroatoms for adsorption to the metal floor and aromatic construction with pi electrons to stabilize its complicated with a steel. The two compounds are exclusive in their chemical characteristics. Sulfadoxine has a systemic title, benzenesulfonamide, a molecular components of C12H14N4O4S with a molecular mass. While Pyrimethamine has a systemic-IUPAC identify pyrimidinediamine, a molecular formula of molecular excess weight Corrosion difficulties have been examined by implementing different methods which such as fuel-metric, gravimetric, thermometric, surface homes and electrochemistry approaches. Researchers have applied these approaches in knowing the system of corrosion and its inhibition for equally normal and artificial inhibitors. Gravimetric approach has been utilized to examine the corrosion inhibition properties of Nypa fruticans wurmb extract and diphenylcarbazone.