Since WWTPs can remove IBP from waters with inadequate efficiency, new research efforts are currently being made to find novel and efficient treatments to be integrated within the WWTP schemes. A first line of activities includes the transformation of IBP into harmless compounds through photocatalysis , Chemical Atazanavir , Fenton processes  and , ozonation , sonochemical degradation  and cavitation . All these applications have been put forward only recently and, even if the results are promising, there is still some uncertainty at the genesis of degradation compounds and by-products, which should be further investigated. In order to overcome this drawback and to work out an effective depuration technology, a second line of investigation refers to the application of adsorption processes, mainly conducted on either natural materials  or activated carbons , ,  and .
Adsorption has been widely used for water, groundwater or wastewater treatment, because endothermic combines good efficiencies with a reliable and robust process configuration  and . It is a very versatile process that can be used for organic compounds and heavy metal capture thanks to a wide spectrum of adsorption targets ,  and  as well as for single or multiple contaminations  and . The wide application of the adsorption process is also due to the possibility of using different kinds of adsorbents, including natural and waste materials either raw or activated , ,  and .