2. Materials and methods
2.1. Procedure and setup
Measurement circuit Sorafenib Tosylate shown schematically in Fig. 1. We used the AT-cut quartz Plates 8.25 mm in diameter (QCM), at resonance frequency of 14.3 MHz (Morion, St. Petersburg, Russia). The harmonic voltage U0 with smoothly varied amplitude (from 0 to 10 V during 30–120 s) with QCM frequency is supplied from the generator (Frequency Generator).