External traumatic impacts to midface such as blunt injuries can

To find a proper material for orbital floor reconstruction is not an easy task. The first material to be routinely used for orbital floor repair was silicone in the form of flexible sheets (commercially named Silastic®), introduced in the 1960s by Lipshutz and Ardizone [8]. Since then, a wide number of substances of biological or synthetic origin have been experimented in the hope that everolimus a truly functional biomaterial will eventually materialize. A special subset of ceramics and composites appear to be highly suitable due to their favourable physico-mechanical properties and, in some cases (e.g. HA, bioactive glasses), osteogenic potential sternum promotes bone regeneration ( Table 1). Ceramic and composite implants for orbital bone repair can be fabricated in the form of dense plates/sheets or porous structures; in the latter case, pore features typical of bone tissue engineering scaffolds are recommended (porosity above 50 vol%, macropore size of at least 100 μm, high pore interconnectivity) [9] and [10].