Biology Of Wound Healing
Anyone who remembers his cara untuk menghilangkan komedo scrapes offers probably heard often 'Don't pick that scab, you'll simply make it worse!'.
Tissue damage triggers a quick bloodstream clotting, and wounds are repaired by the creation of new epidermal cells.
When you remove a scab, you are also eliminating a few of the newly regenerated tissues growing underneath, thereby messing with the healing mechanism.
What is Wound Healing?
A tissue wound via an incision is usually followed by bleeding.
The procedure of vasoconstriction and starts with clotted blood quickly impregnating the wound, leading to hemostasis, and after dehydration, a scab forms.
An influx of inflammatory cells follows, with the liberation of cellular secretions and mediators.
Angiogenesis (growth of arteries) and occurs and the accumulation of fresh new cellular and extracellular elements ensues.
The Wound Healing Mechanism in detail
Wound healing is a complicated and dynamic mechanism of reconstruction of skin cell structures and cells layers.
The mechanism of wound recovery is made from various steps that lead to the formation of scar tissue in replacement of tissue that has been damaged.
The human adult wound healing mechanism can be studied into 3 great different phases:
1- the inflammatory phase 2- the fibroblastic stage 3- the scar maturation phase
The inflammatory phase occurs immediately after the injury and lasts about 6 days.
The fibroblastic phase happens at the termination of the inflammatory stage and will last approximately 4 weeks.
Scar maturation begins at the first month and can last for years.
These three phases include various procedures: chemotaxis (attraction of cells by chemical substances), phagocytosis, neocollagenesis, collagen degradation, and collagen remodeling.
Also, angiogenesis (restored cappilaries), epithelization, and the synthesis of fresh glycosaminoglycans (GAGs) and proteoglycans are crucial to the wound healing sphere.
The culmination of the biological processes results in the replacement of normal skin elements with fibroblastic mediated scar tissue.
This mechanism can create an exuberance of fibrous protein synthesis with a resultant hypertrophic scar, which by definition is normally confined to the wound region. Further exuberance can result in keloid development where scar synthesis extends beyond the region of the original damage. Conversely, insufficient healing can lead to atrophic scar formation like in stretch marks.
How to improve the Wound Healing Mechanism?
Copper & Zinc as trace elements play an important role in the healing of acne lesions and in wound healing. These molecules and elements act as biological activators of both the elimination of dead and wounded pores and skin cells and the rejuvenation of healthful cells. And in addition destroy opportunistic micro-organisms that thrive in wounds, while at exactly the same time reconstructing the web of arteries that enhance oxygenation and nutrition into the newly formed healthy cells.