Fig. 7. Endothelial cell morphology at day 1: (a) unimplanted TiN coating, (b) 0.5 h Pr implanted TiN coating, and (c) 1 h Pr implanted TiN coating. The endothelial cell spread on all the samples after 6 days: (d) unimplanted TiN coating, (e) 0.5 h Pr implanted TiN coating forming avascular tissue-like network in vitro, and (f) 1 h Pr implanted TiN coatings.Figure optionsDownload full-size imageDownload high-quality image (706 K)Download as PowerPoint slide
The cell morphology and functions Abiraterone acetate related. The morphology changes after cell necrosis, aging, damage, and so on and so the cell morphology is an important index of cytocompatibility . Our cell proliferation experiments show that the two Pr implanted samples do not harm vascular endothelial cells that can adhere and proliferate on the surface. The observed cytoskeleton and morphology of the vascular endothelial cells are normal indicative of normal physiological functions. Vascular endothelial cells have many important physiological functions such as anticoagulation, blood clotting, vasodilatation, etc . Our results indicate the Pr implanted TiN coatings maintain the normal functions of the blood vessel inner wall while the corrosion resistance is improved.