So, Who Hopes For A Piece Of GDC-0941?

Magnetic, supported acidic ionic liquid wasSelumetinib (AZD6244) synthesized and recognized as an effective catalyst for that one-pot synthesis of novel spirooxindole derivatives at mild conditions and in superior yields. 3 element reaction of wide range of substituted isatins, one,3-dimethyl-2-amino STAT signaling uracil, and barbituric acid, thiobarbituric acid, and dimedon as 1,3-dicarbonyl compounds gives the target compounds. Operational simplicity, reduced value, higher yields, environmental friendliness, wide applicability and reusability and easy recovery in the catalyst employing an external considering magnet would be the critical functions of this methodology.