GSH content decreases as the age increases, leaving more ROS and toxic chemicals that are harmful to the cells. ROS and toxic chemicals further break homeostasis, and weaken immunity system. Consequently, the reduction of cell viability and physiological function become more drastic. It may explain why older people are more vulnerable to diseases.
GSH level in erythrocytes with people of different pathological states
Fig. 5. The electropherograms of GSH content in erythrocytes from people with chronic diseases.