The GR CALUX bioassay mdash a human osteosarcoma cell

Table 2.
3.3. GR agonistic activities in effluents
Fig. 3. Dose-dependent agonistic response of sewage treatment plant (STP) effluent extracts collected in Japan in Simvastatin GR-CALUX bioassay. Values represent mean ± S.D. from three independent assays. Dex: dexamethasone.Figure optionsDownload full-size imageDownload as PowerPoint slide
Fig. 4. GR agonistic activities in effluent extracts from sewage treatment plants (STPs) located in Ehime (EE), Kyoto (KE-1 to -4), Osaka (KE-5 to -8), and Hyogo (KE-9) in Japan. Effluent samples were collected in May (black circles), July (gray circles) and December (white circles) 2012. Values represent the means from three independent assays. In hypertension study, the LOD was 3.0 ng Dex-EQ L− 1 for STP effluent samples.Figure optionsDownload full-size imageDownload as PowerPoint slide
Table 3.
3.4. Quantitative evaluation of GC contribution to total GR agonistic activity
3.5. Implication of the obtained results