Silver Standards

Calcd For C23H16C12F2N2O: C, 62.04; H, three.62; N, 6.29; Uncovered: Axl C, 62.08; H, 3.64; N, 2.23.4.1.5. Calcd For C24H22N2O: C, 81.33; H, 6.26; N, 7.90; Located: C, 81.forty; H, six.23; N, 7.95.4.1.six.

8-(2-chlorobenzylidene)-2-amino-4-(2-chlorophenyl)-6-methyl-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (Entry 14, 3n) Cream powder, IR(KBr): 3472, 3330, 2945, 2924, 2192, 1674, 1635, Blebbistatin molecular weight 1594, 1411, 1130, 1036, 738cm?one; 1HNMR (250MHz, CDCl3): �� = 0.85 (d, 3H, J = 6.2Hz, CH3), 1.53�C1.87 (m, 2H, CH2), one.96�C2.17 (m, 2H, CH2), two.59�C2.65 (m, 1H, CH), four.62 (s, 1H, CH), four.69 (s, 2H, NH2), six.92 (s, 1H, =CH), seven.25�C7.43 (m, 8H, ArH); 13CNMR (62.9MHz, CDCl3): �� = twenty.90, 28.81, 35.10, 35.fifty five, 39.69, 59.24, 119.63, 120.19, 126.27, 127.61, 128.30, 128.59, 129.49, 129.77, 130.46, 130.68, 133.48, 134.08, 135.24, 135.55, 139.84, 140.89, 141.31, 159.36. Calcd For C24H20Cl2N2O: C, 68.09; H, 4.76; N, six.62; Observed: C, 68.0; H, four.78; N, six.58.4.1.7.

8-(4-chlorobenzylidene)-2-amino-4-(4-chlorophenyl)-6-methyl-5,six,seven,8-tetrahydro-4H-chromene-3-carbonitrile selleck chemical (Entry 15, 3o) Cream powder, IR(KBr): 3423, 3329, 2925, 2190, 1672, 1636, 1590, 1483, 1409, 1126, 1010, 823cm?one; 1HNMR (250MHz, CDCl3): �� = 0.88 (d, 3H, J = 6.0Hz, CH3), one.55�C2.45 (m, 4H, 2CH2), two.75�C2.80 (m, 1H, CH), three.93 (s, 1H, CH), 4.62 (s, 2H, NH2), six.82 (s, 1H, =CH), seven.14�C7.34 (m, 8H, ArH); 13CNMR (62.9MHz, CDCl3): �� = twenty.97, 28.86, 34.64, 35.07, 43.39, 60.05, 114.36, 114.48, 119.76, 121.85, 128.43, 128.98, 129.29, 130.52, 132.64, 135.34, 141.16, 141.56, 158.90, 158.99. 8-(4-methoxybenzylidene)-2-amino-4-(4-methoxyphenyl)-6-methyl-5,six,7,8-tetrahydro-4H-chromene-3-carbonitrile (Entry17, 3q) Cream powder, IR(KBr): 3461, 3323, 2924, 2846, 2194, 1671, 1635, 1593, 1417, 1124, 845cm?1; 1HNMR (250MHz, CDCl3): �� = 0.

88 (d, 3H, J = 5.7Hz, CH3), 1.60�C2.17 (m, 4H, 2CH2), two.81�C2.87 (m, 1H, CH), 3.80 (s, 3H, OCH3), 3.83 (s, 3H, OCH3), 3.90 (s, 1H, CH), 4.51 (s, 2H, NH2), six.81 (s, 1H, =CH), six.85�C6.92 (m, 4H, ArH), seven.13�C7.26 (m, 4H, ArH); 13CNMR (62.9MHz, CDCl3): �� = 21.08, 28.50, 28.97, 35.25, 36.06, 43.09, 55.28, 60.83, 113.68, 114.09, 120, 122.ten, 127.31, 128.forty, 128.95, 129.56, 130.56, 135.ten, 141.10, 158.42, 159.24, 159.83. Anal. Calcd For C26H26N2O3: C, 75.34; H, 6.32; N, six.76; Identified: C, 75.37; H, six.28; N, six.73.