Psychology. - Free Online Library

PD149163, a putative atypical antipsychotic drug. Bree-Ona Ebrecht,Elizabeth Holly, Amber LaCrosse, and Adam J. Prus, Northern MichiganUniversity, Department of Psychology

Atypical antipsychotic drugs are regarded as superior to typical antipsychotic drugs, in regard to improved efficacy for negative symptoms and lack of extrapyramidal side effects at therapeutically effective doses, for the treatment of schizophrenia. Both classes of antipsychotic drugs treat positive symptoms. Atypical antipsychotic drugs may derive their improved efficacy, in part, through enhanced dopamine release in the prefrontal cortex. The present study was conducted to determine if