Fig xA Protein electrophoresis diagram of the
According to the external appearance, the tire mark on the back consisted of wavy parallel lines. They were sharply defined and had a carmine-red hue as it is typical of blood extravasations in the upper corium layers . When looked at with a magnifying glass, the red IPI-504 discolorations were composed of individual or confluent petechial bleedings located closely together. On the right lower back, where the intradermal hemorrhages were especially pronounced, the skin was also blistered in congruence with the red-colored stripes. The blisters were strictly confined to the bruised areas and had a maximum diameter of 15 mm. They contained up to 0.5 ml of yellowish serous fluid.
The histological examination confirmed that the patterned bruises were caused by blood extravasations in the upper corium (stratum papillare, Fig. 4). The blistered parts of the skin (Fig. 5) showed a dome-like detachment of the epidermis, which enclosed a homogeneous eosinophilic fluid without erythrocytes or other cellular elements. In most cases, the liquid content had got lost due to the preparation procedure. The skin specimens that had been subjected to fat staining revealed the presence of extracellular fat in the connective tissue of the corium and even in the blister cavities where the fluid was interspersed with droplets of fat.