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Polycomb group proteins (PcGs) create chromatin-modifying complexes that regulate gene expression. PcGs are categorized into two main groups, polycomb repressive complicated 1 (PRC1) selleck OSI-027 and 2 (PRC2), which have classically been imagined to function with each other. Right here we talk about current information demanding this model indicating that the distinct subunit composition of PRC1 confers distinct and nonoverlapping functions inAdenosine Receptor embryonic and adult stem cells.