How To Kickstart C-X-C chemokine receptor type 4 (CXCR-4) Within Three Secs

The cell cycle C-X-C chemokine receptor type 4 (CXCR-4) (CXCR-4)} regulators involved in maintaining the quiescence, and therefore the self-renewal capability, of somatic stem cells have extended been elusive. Two new Cell Stem Cell posts in this issue (Matsumoto et al., 2011; Zou inhibitor price et al., 2011) now display that the CDK inhibitor p57 is a vital brake for cycling HSCs, and backlinks self-renewal activity to cell cycleselleck products quiescence.