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Using nitrous oxide in modern anaesthesia is questioned. We surveyed changes in use of nitrous oxide in Scandinavia and its justifications during the last two decades.


All CRM1 191 departments of anaesthesia during the Scandinavian countries have been requested by e mail to reply an electronic survey in SurveyMonkey.


One hundred and twenty-five (64%) in the departments responded; 4 had been excluded. The 121 departments offered 807.520 general anaesthetics annually. The utilization of nitrous oxide was reported in eleven.9% of instances, ranging from 0.6% in Denmark to 38.6% in Iceland when volatile anaesthetics have been employed in 48.9%, lowest in Denmark (22.6%) and highest in Iceland (91.9%). Nitrous oxide was co-administered with volatile anaesthetics in 21.

5% of standard anaesthetics [2.4% (Denmark) -34.5% (Iceland)]. Utilization of nitrous oxide was unchanged in five departments (4%), reducing in 75 (62%) and stopped in 41 (34%). Causes for reducing or stopping utilization of nitrous oxide were fairly uniform within the 5 countries, the most crucial currently being that other agents had been 'better',selleck inhibitor whereas couple of place weight on its potential chance for escalating morbidity. Choice to prevent making use of nitrous oxide was produced through the departments except in 4 instances. Of 87 maternity wards, nitrous oxide was utilized in 72, whereas this was the case in 42 of 111 day-surgery units.


The use of nitrous oxide has selleck chemicals AT9283 decreased while in the Scandinavian nations, apparently because a lot of now want other agents. Big difference in practices between the five nations had been sudden and apparently not justified on anticipated evidence only."