3-Deazaneplanocin In a later study Fontes Lima et al compared

For this type of reactor, operations of 60 days can be considered long-term because within this period is sufficient to evaluate the biochemical pathways that are primarily responsible for operating instabilities and to evaluate possible hydrodynamic sickness resulting from the accumulation of biomass in the packed bed. Moreover, in most operations using this type of reactor configuration, decreases in hydrogen production have been observed at an early stage (i.e., from the 25th day of operation).