Biology Of Wound Healing
Anyone who remembers his cara untuk menghilangkan komedo di hidung scrapes has probably heard many times 'Don't choose that scab, you'll just make it worse!'.
Tissue damage triggers a quick blood clotting, and wounds are repaired by the creation of new epidermal cells.
When you remove a scab, you are also eliminating some of the newly regenerated tissues growing underneath, thereby messing with the healing system.
What is Wound Healing?
A cells wound via an incision is usually followed by bleeding.
The procedure of vasoconstriction and coagulation starts with clotted blood quickly impregnating the wound, resulting in hemostasis, and after dehydration, a scab forms.
An influx of inflammatory cells follows, with the liberation of cellular secretions and mediators.
Angiogenesis (growth of arteries) and re-epithelization occurs and the
of fresh new cellular and extracellular parts ensues.
The Wound Healing Mechanism in detail
Wound healing is a complex and system of reconstruction of pores and skin cell structures and tissue layers.
The mechanism of wound recovery is made of various steps that result in the formation of scar tissue formation in replacement of tissue that is damaged.
The human adult wound recovery mechanism could be studied into 3 great different phases:
1- the inflammatory phase 2- the fibroblastic phase 3- the scar maturation phase
The inflammatory phase occurs soon after the injury and lasts approximately 6 days.
The fibroblastic phase takes place at the termination of the inflammatory phase and will last approximately 4 weeks.
Scar maturation starts at the first month and will last for years.
These three phases include various procedures: chemotaxis (attraction of cells by chemical compounds), phagocytosis, neocollagenesis, collagen degradation, and collagen remodeling.
Also, angiogenesis (restored cappilaries), epithelization, and the formation of fresh glycosaminoglycans (GAGs) and proteoglycans are essential to the wound healing sphere.
The culmination of these biological processes results in the replacement of normal skin elements with fibroblastic mediated scar tissue.
This mechanism can produce an exuberance of fibrous proteins synthesis with a resultant hypertrophic scar, which by definition is confined to the wound area. Further exuberance can result in keloid formation where scar synthesis extends beyond the area of the initial damage. Conversely, insufficient healing can result in atrophic scar development like in stretch marks.
How to improve the Wound Healing Mechanism?
Copper & Zinc as trace elements play an important role in the recovery of acne lesions and in wound healing. These molecules and elements become biological activators of both elimination of dead and injured pores and skin cells and the rejuvenation of healthy cells. And in addition destroy opportunistic micro-organisms that thrive in wounds, while at the same time reconstructing the web of arteries that enhance oxygenation and diet into the newly formed healthy cells.