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Tags within selleck ABT-378 the detection range were assumed to be always detected by a reader without signal strength information. A reader was considered to move randomly in each space, and the position of the reader was determined by the k-NN algorithm with the same weight for each detected tag. The optimal detection range was calculated, in the analytical and numerical approaches, by minimizing the RMSE. Here, the analytical approach indicates a mathematical proof, and the numerical approach, a simulation. In 1-dimensional space, both the analytical and numerical approaches were employed. In the 2-dimensional and 3-dimensional spaces, only the numerical approach was used, owing to its complexity. Figure 1 represents the concept of the simulation in 2-dimensional space.Figure 1.Concept of simulation in a 2-dimensional space.

3.2. 1-Dimensional Space3.2.1. Analytical ApproachFigures 2a and 2b illustrate the analytical approach in 1-dimensional space. The RFID tags are evenly spaced by a tag space b on a line, and a reader can be regarded as moving from 0 and b.Figure 2a.Model of analytical approach in 1-Dimensional space (0 �� a < b/2). Figure 2b. Model of analytical approach in AMPK 1-Dimensional space (b/2 �� a < b).Here, section [0, b] can stand for all of the other sections [k*b, k*(b+1)], where k is an integer, without losing generality. The detection range was defined as Equation 5, based on the assumption that the detection range should be equal to or longer than b:Detection range(R)=nb+a(0��a

Section [0, b] was divided selleck chemical Fulvestrant into sub-sections and the coordinate of the detected tags can be estimated using the k-NN algorithm. Tables 1a and and1b1b show the estimated coordinate for each section.Table 1a.Estimated coordinates from analytical approach (0 �� a < b/2).Table 1b.Estimated coordinates from analytical approach (b/2 �� a < b).The optimal detection range can be resolved, as shown in Equation 6, when the error term of the RMSE is minimized:��0b(xtrue?xmeasurement)2dx��min(6)Using the values shown in Tables 1a and and1b,1b, Equation 6 can be rewritten as:��0b(xtrue?xmeasurement)2dx=��0a(x?0)2dx+��ab?a(x?b2)2dx+��b?ab(x?b)2dx=[x33]0a+[(x?b2)33]ab?a+[(x?b)33]b?ab=b[(a?b4)2+b248](7a)��0b(xtrue?xmeasurement)2dx=��0b?a(x?0)2dx+��b?aa(x?b2)2dx+��ab(x?b)2dx=[x33]0b?a+[(x?b2)33]b?aa+[(x?b)33]ab=b[(a?3b4)2+b248](7b)Equation 7a is minimized to b3/48, as shown in Figure 3a, when a is b/4 and the opt

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