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Figure 1 Yearly distribution of facial fractures. The patients' Paclitaxel age ranged between 1 and 89 years, with a mean of 37.6 and a median of 33 (Fig. 2). Among the patients 40.2% were between 16 and 30 years. The mean and the median were, respectively, 35.9 and 31 in males and 45.9 and 45.5 in females. The median was 13.5 years higher in females (statistically significant difference, p<0.001). The facial fracture incidence peak was different in males and females: the majority of fractures in males occurred between 16 and 30 years, the frequency decreasing with age after that; females, nevertheless, suffered more fractures between 31 and 45 years, the risk being inversely related to age, but maintaining higher relative risks than males older than 45 years. In males, 71.

2% of all fractures occurred in those younger than 46 years, whereas in females 50% of fractured occurred in those older than 45. Figure 2 Number of fractures related to age done group. Regarding fracture type, zygomatic complex fractures accounted for 33.2%, mandible fractures for 32%, and orbit fractures for 24.5%; 4.8% were Le Fort fractures; 2%, panfacial fractures; 1.9% frontal fractures; and 1.6% NE complex fractures (Fig. 3). Of the total number of patients, 25% had at least two associated fractures: the most common association were orbit and malar (18.9% of all patients), followed by malar and mandible (6%). Figure 3 Distribution of the fractures according to fracture type. In this study, the major cause of injury was traffic accidents (27%, 6.7% of them were motorcycle accidents), which was followed by other causes such as assaults (20.

5%), accidental traumas (20.1%), sports-related accidents (11%), syncopes (7.8%), rural accidents (6.1%, of which 3.3% were machinery-related LY2157299 purchase and 2.8% related to domestic animals), industrial accidents (5.1%), suicide attempts (0.3%); in 1.1% of the patients, it was impossible to ascertain the etiology, due to an incomplete medical history and to the inability to contact the patient (Fig. 4). Figure 4 Distribution of the fractures in relation to etiology. The male:female ratio for each cause was always higher than 1, ranging from 43 in assaults, 9.7 in motorcycle accidents, and 7.9 in sports, to 2.3 in syncopes and 2.1 in accidental traumas. There was no fracture due to industrial accidents in females.

Comparing the most common causes in each age interval, we observe that under 16 years, the main causes were sports (37.1%) and traffic accidents (25.7%); between 16 and 60 years, traffic accidents; and over 60 years the cause was predominantly accidental traumas (Fig. 5). We have found statistically significant differences in the following aspects: sports-related fractures decreased with age and the frequency of accidental traumas increased in a direct proportion with the age of the patient (p<0.001 for both significances); industrial accidents and assaults were more common in males (p<0.016 and 0.