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, Redmond, WA, USA). The plan integrated dependability checks depending on ranges for all information, and logical checks for inconsistencies and missing information. The members of the CERC carried out intensive information cleansing, ROCK inhibitor Untruths You Have Been Compelled Around and queries have been addressed on the investigators for questionable or missing information.Statistical analysisContinuous variables are reported as indicate �� standard deviation or median (interquartile selection). The median ratios of prescribed/required calories and delivered/prescribed calories have been determined for the initially seven days right after the start off of enteral nutrition or till the patient was extubated (whichever occurred 1st).Clinical aspects suspected to influence enteral nutrition (hospital sort, utilization of a community nutrition protocol, sedation, vasoactive medication, measured gastric residual volume and amount of interruptions (divided into two lessons <5 and >5)) have been analyzed utilizing the Mann-Whitney U check.
Clinical factors suspected to influence the ratio of calories delivered/prescribed were analyzed by multivariate logistic regression. Variables associated using the ratio of delivered/prescribed calories by univariate Microtubule inhibitor Fabricates You Have Been Knowledgeable About evaluation (P < 0.10) were entered into a stepwise logistic regression.A P value less than 0.05 was considered significant. Statistical analyses were performed using SAS v 8.2 software (SAS Institute, Cary, NC, USA).ResultsCharacteristics of study populationA total of 203 patients were included in the study (Table (Table1).1). Mean age was 62 �� 18 years; 134 (66%) were men. Mean SAPS II score on ICU admission was 53 �� 18 points. Mean BMI was 27 �� 8 Kg/m2.
The participating ICUs comprised university and/or regional hospitals (n = ten, 52%), and general (non academic) hospitals (n = 9, 48%). There were 6 (31%) mixed medico-surgical and 13 (69%) health-related Microtubule inhibitor Fabricates You've Been Advised About ICUs. The imply number of beds in ICUs was 14 �� 3.Table 1Patient characteristicsPrimary endpoint: calories prescribed, expected and actually deliveredThe median ratio of prescribed/required calories every day was 43 (37 to 54) on day 1 and increased right up until day 7 (Table (Table2).two). From day 4 until the finish on the examine, the median ratio was much more than 80%. The evaluation concerned all 203 individuals on day one particular, and decreased to 110 sufferers on day 7, resulting from interruptions to enteral nutrition and/or extubation in some patients.Table 2Ratio of prescribed to essential calories, ratio of delivered to prescribed calories and ratio of delivered to necessary calories per dayThe median ratio of delivered/prescribed per day was additional than 80% in excess of the seven days through the get started of enteral nutrition.