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He suffered a extreme head injury with penetrating comminuted bilateral frontal sinus fractures´┐Ż´┐Żaffecting each anterior and posterior walls, with epidural hematoma, brain contusion, and cerebrospinal fluid (CSF) leak; other trauma included posterior arch fracture of C2 and C3; correct comminuted fractured femur LY3009104 and stomach trauma with hemoperitoneum, mesocolon tear, and pancreatic contusion. Reduction and osteosynthesis on the femur fracture, laparotomy and bifrontal craniotomy with hematoma evacuation, dural repair, frontal sinus cranialization, and also a unwanted fat graft for that skull base defect were carried out in the regional hospital. A single month later, the patient was discharged and presented to our department, with bilateral frontal and orbital cellulitis, frontal osteomyelitis with bone sequestration, and an epidural abscess (Figs.

1 and ?and2).two). The preliminary surgical treatment method integrated sequestrectomy and curettage with the infected bone. Nasoethmoidal-orbital fracture was stabilized with transnasal wiring, plus the medial canthal tendons have been repaired employing bilateral transnasal canthopexy. Reconstruction which has a temporalis muscle flap was at first performed to seal the anterior cranial fossa defect (Fig. 3). Galeal selleck products or galeal-pericranial flaps were not achievable at that time due to the first soft tissue injury and continual infection. Frontal bone reconstruction was accomplished utilizing bone fracture fragments with fixation using the Synthes (Solothurn, Switzerland) one.3-mm technique of titanium miniplates and screws (Fig. 4).

Figure 1 Clinical Mammalian target of rapamycin photograph demonstrating frontal and orbital cellulitis with cutaneous fistulization and posttraumatic orbital hypertelorism. Figure 2 CT scans showing bilateral nasoethmoid orbital fractures plus a frontal pneumoencephalus relevant for the frontal bone fracture. Figure 3 Intraoperative view; patient supine and images taken from a cranial perspective. (A) Exposure of frontal bone immediately after elevation with the cutaneous flap (*, nasal bones). (B) Epidural abscess and frontonasoethmoid ... Figure four Frontal bone reconstruction (T, temporalis muscle). Two months right after the 2nd surgical procedure, the patient formulated recurrent bilateral frontal osteomyelitis with fronto-orbital cellulitis. Cultures from the necrotic bone revealed the presence of Pseudomonas aeruginosa. Systemic antibiotic treatment and neighborhood debridement have been not fully efficient.

Thus, a extra in depth surgical debridement was performed. The bone through the initial bifrontal craniectomy as well as the fronto-orbital bar were removed. The defect was to start with sealed by using a rectus abdominis free flap (Fig. five). Anastomoses have been performed on the external carotid artery and thyrolingual trunk. Frontal bone reconstruction was performed in the 2nd stage 1 year later applying a custom-made difficult tissue replacement (HTR) alloplastic implant (Biomet, Warsaw, Indiana) intended from computerized reconstruction (Fig. 6).