Finally our findings cannot be

Unweighted and weighted patient characteristics according to whether or not they NPPB received CDSUnweighted comparisonPropensity score-weighted comparison*No CDS (n=1558)CDS (n=269)p valueNo CDSCDSp valueAge (years)Mean (SD)70·3 (12·5)64·6 (12·0)<0·000169·5 (12·6)68·6 (12·1)0·26Median (IQR)72 (63–80)65 (57–72)<0·000171 (62–79)71 (62–78)0·90Sex0·490·51Male915 (59%)164 (61%)921 (59%)166 (62%)Female643 (41%)105 (39%)637 (41%)105 (39%)Primary cancer site0·550·98Lung332 (21%)65 (24%)339 (22%)56 (21%)Gastrointestinal420 (27%)79 (29%)425 (27%)74 (28%)Liver, pancreas, biliary system327 (21%)50 (19%)322 (21%)62 (23%)Breast77 (5%)8 (3%)72 (5%)12 (4%)Gynaecological87 (6%)17 (6%)89 (6%)16 (6%)Urological97 (6%)18 (7%)97 (6%)14 (5%)Others218 (14%)32 (12%)213 (14%)37 (14%)Any metastasis1248 (80%)236 (88%)0·00311265 (81%)223 (82%)0·68ECOG performance status0·000570·710–2332 (21%)71 (26%)342 (22·)54 (20%)3580 (37%)120 (45%)598 (38%)103 (38%)4646 (41%)78 (29%)618 (38%)113 (42%)Normal abbreviated mental test score (4 or higher)1085 (70%)221 (82%)<0·00011113 (71%)191 (71%)0·74Chemotherapy within 1 month678 (18%)72 (27%)0·00059298 (19%)52 (19%)0·98SymptomsDyspnoea492 (32%)90 (33%)0·54497 (32%)87 (32%)0·95Fatigue1195 (77%)189 (70%)0·0231180 (76%)205 (76%)0·97Delirium400 (26%)48 (18%)0·0058382 (25%)68 (25%)0·84Inability to transfer997 (64%)142 (53%)0·00046971 (62%)169 (63%)0·99Pleural effusion246 (16%)57 (21%)0·028258 (17%)42 (16%)0·66Artificial hydration before death0·14NANone646 (41%)102 (38%)NANA<1 L/day769 (49%)149 (55%)NANA≥1 L/day143 (9%)18 (7%)NANAPlace of care0·0980·82Hospital512 (33%)106 (39%)528 (34%)96 (35%)Palliative care unit683 (44%)103 (38%)669 (43%)111 (41%)Home363 (23%)60 (22%)361 (23%)64 (24%)Data are biome mean (SD) or n (%) unless otherwise specified, and compared by the unpaired t test or χ2 test as appropriate. All characteristics were recorded at enrolment, apart from articifical hydration before death. CDS=continuous deep sedation. ECOG=Eastern Cooperative Oncology Group. NA=not applicable (treatment variable not entered into the propensity model).*Weighted by inverse probability of treatment weighting estimation to balance patient characteristics.Full-size tableTable optionsView in workspaceDownload as CSV