Use of ondansetron in children with gastroenteritis.
DeCamp LR, Byerley JS, Doshi N, Steiner MJ. However, vomiting from gastroenteritis is distressing to
patients and their families. In 11 included studies,
seven different antiemetics were evaluated, and children who received
ondansetron were less likely to have on-going vomiting, be prescribed
intravenous feeding, or be admitted to hospital from the emergency
department. All rights reserved.
. Many physicians also believe that vomiting
is a contraindication to ORT.
To determine whether antiemetics reduce vomiting and decrease need
for further intervention without significant adverse effects, University
of North Carolina researchers performed a systematic review and
meta-analysis of prospective controlled trials evaluating medication use
in children with vomiting from gastroenteritis. Acute
gastroenteritis is a common childhood illness, and guidelines for
treatment recommend supportive care zofran lawsuit charlotte nc using oral rehydration therapy (ORT)
for mild to moderate dehydration, but no pharmacologic treatment for
vomiting. Future treatment guidelines should incorporate ondansetron
therapy for selected children with gastroenteritis, say the authors.
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No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2008 Gale, Cengage Learning. Use of http://www.drugs.com/cdi/zofran.html antiemetic
agents in acute gastroenteritis: a systematic review and meta-analysis.
Archives of Pediatric and Adolescent Medicine, 2008; 162(9): 858-65.
Children with gastroenteritis who receive ondansetron (Zofran) are
less likely to have on-going vomiting, a study has found